You are here: Home Plants Cell-based modeling

Cell-based modeling

Roeland Merks (2015) Cell-based modeling. In: Björn Engquist (Ed.) Encyclopedia of Applied and Computational Mathematics, pp. 195-201. Springer-Verlag Berlin Heidelberg.

A cell-based model is a simulation model that predicts collective behavior of cell-clusters from the behavior and interactions of individual cells.  The inputs to a cell-based model are cell behaviors as observed in experiments or deriving from single cell models, including the cellular responses to cues from the micro-environment. The cell behaviors are encoded in a set of biologically plausible rules that the simulated cells will follow. The outputs of a cell-based model are the patterns and behaviors that follow indirectly from the cell behaviors and the cellular interactions. Cell-based models resemble agent-based models, but typically contain more biophysically-detailed descriptions of the individual cells. In: Björn Engquist (Ed.) (2015) Encyclopedia of Applied and Computational Mathematics, Springer Verlag, Berlin Heidelberg, pp. 195-201 [ preprint ]